Works of fighters a. Information about the personnel of teaching staff of an educational organization. Participation in international conferences

Boytsov A.G. Adhesion of lactobacilli to cells of vaginal and buccal epithelium / A.G. Boytsov, S.V. Rishchuk, Yu.Yu. Ilyasov, T.A. Grechaninova // Bulletin of St. Petersburg Medical Academy them. I.I. Mechnikov. – 2004. – No. 4 (5) – P. 191193. ADHESION OF LACTOBACTERIA TO CELLS OF VAGINAL AND BUCAL EPITHELIA Boytsov A.G., Rishchuk S.V., Ilyasov Yu.Yu., Grechaninova T.A. GOUVPO St. Petersburg State Medical Academy named after. I.I. Mechnikova SUMMARY The adhesion of lactobacilli preparations to the buccal and vaginal epithelium of 24 women in 91 experiments was assessed. The results obtained confirm the specific nature of lactobacilli adhesion. This is probably determined by the degree of homology between the receptors of epithelial cells and bacteria. A high correlation was determined between the degree of adhesion of lactobacilli to two types of epithelium (Spearman's rank correlation coefficient 0.7). From a practical point of view, the need for individual selection of probiotics for replacement therapy of vaginal dysbiosis is confirmed. A simple and convenient method for making such a selection can be the proposed method for determining the adhesion of bacteria to the buccal epithelium. THE RESUME The adhesion of preparations of Lactobacilli valued to buccal epithelial cells and vaginal epithelial cells of 24 women in 91 experiments. The received results to confirm specific character of an adhesion the Lactobacilli. It’s defined prabably a degree of homology receptors of epithelial cells and bacteria. It’s determined the high correlation interrelations between the degree of an adhesion the Lactobacilli to two kinds of an epithelium (the factor of ranking correlations Spirmen 0.7). From the practical point of view to confirm the necessity of individual selection of probiotics attached by replaceable therapy of disbiosis of vaginas. As a simple and a convenient method for exercise of such selection can serve the offered technique of definition of an adhesion of bacteria to buccal epithelial cells. INTRODUCTION It is known that lactobacilli are the main component of the microbial biocenosis of the vagina of an adult sexually mature woman. Their pronounced antagonistic activity towards most foreign microorganisms is one of the main mechanisms ensuring the prevention of the development of vaginitis and vaginosis. It is no coincidence that a decrease in the number of these microorganisms is observed against the background of many pathological manifestations or is one of the causes of almost all types of pathology of this part of the genital tract. According to many researchers, restoring the normal number of lactobacilli is one of the important components of the treatment of vaginosis and vaginitis. For these purposes, it has been repeatedly proposed to use preparations containing live lactobacilli, for example, lactobacterin. The main condition for the effectiveness of such treatment is the attachment of lactobacilli to the cells of the vaginal epithelium. The molecular mechanisms that ensure the adhesion of lactobacilli to vaginal epithelial cells are not completely clear. According to various authors, the lactobacilli receptors responsible for this process are of protein or carbohydrate nature. There is information about the participation of lipoteichoic acids in this process. Possibly receptors different types lactobacilli have a different nature. It can be assumed that the adsorption of lactobacilli is specific and depends on the correspondence of the receptors of a given specific strain of lactobacilli to the receptors of the vaginal epithelial cells of a particular woman. According to the hypothesis of B.A. Shenderov, even during the period of intrauterine development, the child’s body prepares to accept the mother’s microflora as “its own”, or, in other words, it develops immunological tolerance to normal microflora. In addition, it was shown that the adsorption of lactobacilli on the intestinal mucosa depended on the age of the donor. It was established that lactobacilli of vaginal origin attach better to vaginal epithelial cells compared to strains isolated from other sources, for example, food. All of the above suggests that preparations containing lactobacilli and intended for intravaginal use should be selected individually for each woman. This work is an attempt to test a method to achieve this goal. Existing methods for determining the adhesion of lactobacilli to vaginal epithelial cells are, as a rule, quite complex and difficult to reproduce in practical laboratories. We have made an attempt to simplify them as much as possible. in order to make it possible to implement them in almost any diagnostic laboratory with standard equipment and reagent base. One of the objectives of the work was to assess the possibility of using determination of lactobacilli adhesion to the vaginal epithelium using buccal epithelial cells as a test object. MATERIALS AND METHODS The ability to adhere to epithelial cells was studied in lactobacilli isolated from examined women (autostrains) and lactobacilli included in the preparations “Laktobacterin” (NPO “Biomed”, Prem), “Laktobacterin” (NPO “Immunopreparat”, Ufa) , "Vitaflor" (State Scientific Research Institute of Highly Pure Biological Preparations, St. Petersburg), "Acilact" (LLC "Ferment", Moscow Region), "Imbio" (NPO "Microgen", Nizhny Novgorod), "Biovestin Lacto" ("Biovesta" , Saint Petersburg). Autostrains were isolated by inoculating smears from the posterior vaginal vault onto MRS medium, followed by incubation of the cultures under anaerobic conditions. Immediately before the experiment, lactobacilli were washed twice with McIlwain citrate-phosphate buffer, pH 5.4, by centrifugation. A suspension of 106 cells in 1 ml was prepared from the sediment according to the “turbidity standard”. Vaginal epithelial cells were collected from the posterior vaginal fornix by a gynecologist during a routine examination using a Volkmann spoon, after careful removal of mucus with a cotton swab. At the same time, scrapings of the buccal epithelium were taken. The cells were placed in Eppendorf tubes with citrate-phosphate buffer and transported to the laboratory within 2-3 hours. Immediately before the start of the study, epithelial cells were washed by three times centrifugation (1000 rpm - 5 minutes). After washing the sediment, control smears were prepared. To do this, 1 drop of sediment was applied to the surface of a glass slide and distributed into a disk with a diameter of about 1.5 cm. The smears were fixed and stained with an aqueous solution of methylene blue. A sample was considered suitable for further study if, under microscopy (magnification x 900), there were at least 2-3 epithelial cells in each field of view. To study the adhesive activity, 800 μl of a suspension of epithelial cells and 600 μl of a suspension of lactobacilli were added to an Eppendorf tube. The contents of the tubes were thoroughly mixed and incubated for 2 hours at a temperature of 37 °C with periodic re-mixing by inverting the tubes. After incubation, non-adsorbed bacterial cells were removed by washing twice by centrifugation (1000 rpm for 3 minutes). Smears were prepared from the sediment, which, after fixation, were stained with methylene blue. During microscopy of the specimen, the number of bacterial cells attached to the surface of each epithelial cell was counted. At least 50 cells were analyzed in each preparation. The result was expressed as the arithmetic mean number of lactobacilli on the surface of one epithelial cell. Adhesion in parallel to the buccal and vaginal epithelium of 24 women was assessed in 91 experiments. At the same time, “Laktobacterin” (Perm) was used in 24, “Acilakt” in 20, “Biovestin” in 13, “Inbio” in 9, “Lactobacterin” (Ufa) in 9, autostrains in 9, “Vitaflor” in 7 cases . Taken together, the results of 91 experiments showed that in 65 cases the average number of bacteria attached to the vaginal epithelium was greater than to the buccal epithelium, and in 17 cases it was the other way around. In 9 cases, the average number of bacteria attached to the buccal and vaginal epithelium was the same. A strong, significant correlation was observed between the degree of adhesion to two types of epithelium: linear correlation coefficient - 0.74, Spearman rank correlation coefficient - 0.64. The strength of the relationship varied somewhat depending on the type of drug. Thus, if in experiments with lactobacterin the Spearman correlation coefficient was 0.71 (P = 0.001), then in experiments with acylact it was 0.43 (P = 0.078). However, the results obtained indicate the possibility of using an assessment of the degree of adhesion of lactobacilli to the cells of the buccal epithelium to obtain an idea of the adhesive ability in relation to the vaginal epithelium of a particular patient. The above statement is based on a high correlation between the degree of adhesion to two types of epithelium (Spearman's rank correlation coefficient was 0.7). The following drugs had the highest adhesive activity, both in relation to the buccal and vaginal epithelium: Lactobacterin (Perm), Lactobacterin (Ufa), Vitaflor. At the same time, the comparative activity of individual drugs did not coincide in different patients. As an example, we present the test results of three women. The drugs are listed in descending order of activity. Patient Z. – “Vitaflor”, “Lactobacterin” (Ufa), “Lactobacterin” (Perm), “Acilact”, autostrain; Patient F - “Laktobacterin” (Perm), “Laktobacterin” (Ufa), autostrain, “Acilact”, “Vitaflor”; Patient I. - “Lactobacterin” (Perm), “Imbio”, autostrain, “Acilact”. The results obtained confirm the individual specific nature of lactobacilli adhesion, which is apparently determined by the degree of homology of the receptors of epithelial cells and bacteria. From a practical point of view, this confirms the need for individual selection of probiotics for replacement therapy of dysbiosis. A simple and convenient method for making such a selection can be the proposed method for determining the adhesion of bacteria to the buccal epithelium. REFERENCES 1. Golovinsky E.V. Basic research methods used in microbiology // In the book: Experimental Microbiology. - Sofia: Medicine and Physical Education, 1965.- p. 23-39 2. Shenderov B.A. Medical microbial ecology and functional nutrition. Volume 1: Microflora of humans and animals and its functions. M., Grant, 1998; 288.. 3. Brooker, B. E., Fuller R. Adhesion of lactobacilli to the chicken crop epithelium. // J. Ultrastruct. Res.-1975. v.52.- p. 21-31 4. Conway, P. L., Kjelleberg S. 1989. Protein-mediated adhesion of Lactobacillus fermentum strain 737 to mouse stomach squamous epithelium. //J. Gen. Microbiol.-v. 135.- 11751118; 5. Chan R. C. Y., Reid G., Irvin R. T., Bruce A. W., Costerton J. W.. Competitive exclusion of uropathogens from human uroepithelial cells by Lactobacillus whole cells and cell wall fragments. // Infect. Immun..- 1985. – v.47.- p. 84-89 6. Fuller R.. Nature of the determinant responsible for the adhesion of lactobacilli to chicken crop epithelial cells.// J. Gen. Microbiol.- 1975.- v. 87.- p. 245-250 7. Henriksson A., Szewzyk R., Conway P. L. Characteristics of the adhesive determinants of Lactobacillus fermentum 104. //Appl. Environ. Microbiol..- 1991.-v. 57.- p. 499-502; 8. Kirjavainen P. V., Ouwehand A. C., Isolauri E., Salminen S. J. The ability of probiotic bacteria to bind to human intestinal mucus. FEMS. // Microbiol. Lett. 1998 167:185–189]. 9. Soledad Boris,1 Juan E. Suárez,1 Fernando Vázquez,2 and Covadonga Barbés 10. Soledad Boris,1 Juan E. Suárez,1 Fernando Vázquez,2 and Covadonga Barbés Adherence of Human Vaginal Lactobacilli to Vaginal Epithelial Cells and Interaction with Uropathogens.- Infect Immun, May 1998, p. 1985-1989, Vol. 66, No. 5. 11. Wadström, T., K. Andersson, M. Sydow, L. Axelsson, S. Lindgren, and B. Gullmar. 1987. Surface properties of lactobacilli isolated from the small intestine of pigs. J. Appl. Microbiol. 62:513–520 12. Wood, J. R., R. L. Sweet, A. Catena, W. K. Hadley, and M. Robbie. 1985. In vitro adherence of Lactobacillus species to vaginal epithelial cells. J. Obstet. Gynecol. 153:740-743,

Vasily Vasilievich Boytsov (1908-1997)

Vasily Vasilievich Boytsov (1908-1997). Vasily Vasilyevich Boytsov was born in the village of Alabino, Naro-Fominsk district, Moscow region. He began his career as a stamper in a fishing artel. Next - technical school, then Moscow Higher Technical School. Bauman. 27 years of work in aviation industry, where he went through almost all the steps of the career ladder from an engineer and shop manager to one of the industry leaders and director of the largest research institute - the Research Institute of Technology and Organization of Aviation Production.

Having become the chairman of the Committee on State Standards in 1963, V.V. Boytsov gave standardization work a dynamic, modern character. On his initiative, several research institutes for standardization were created, including the All-Union Scientific Research Institute of Standardization (VNIIS) and the All-Union Scientific Research Institute of Classification, Terminology and Quality Information (VNIIKI), the work of the committee apparatus was reorganized, product certification was introduced for the State Quality Mark, which contributed to the development of work in the field of theory and practice of quality assurance. From 1977-1979 he headed the International Organization for Standardization (ISO).

V. V. Boytsov was awarded many government awards: three Orders of Lenin, Orders of the October Revolution, Red Banner of Labor, Red Star, Patriotic War II degree, “Badge of Honor”, medals.

Having left the post of chairman of Gosstandart in 1984, Vasily Vasilyevich continued to work as a scientist who had vast industrial experience and unconditional authority. He was elected honorary president of the Academy of Quality Problems. The extensive scientific work he carried out throughout his life was reflected in more than 150 publications. He brought his wealth of experience and scientific knowledge to the student classrooms of MAI, MATI and Moscow Higher Technical University named after. N.E. Bauman. Under the leadership of V.V. Boytsov has trained dozens of doctors and candidates of science.

The most important link in the creative heritage of V.V. Boytsov was the development of methods for typing technological processes based on a scientifically based classification of production objects and their automation. These issues were addressed, in particular, in the context of quality research production processes specific enterprise - the machine-building complex as a unique technical system. Noting the strengthening in science and production of complex technical systems and relying on global and domestic experience, V.V. Boytsov predicted that the predominant type of engineering production in the near future will not be mass production in its traditional sense (mass production of a small range of products with a stable design), but the production of a wide range of constantly updated products, homogeneous only in the main design and technological parameters, a range of diverse products and models produced by one plant will invariably increase.

Considering the problems of organizing quality management of mechanical engineering products, V.V. Boytsov emphasized the growing importance of the cybernetic approach to solving the problem of quality, the essence of which is to combine disparate activities into unified system purposeful, constantly carried out actions at all stages of the product life cycle. The organization of product quality management from the perspective of the cybernetic approach can be considered, according to the scientist, in two aspects: structural and functional.

Studying the methodological foundations of quality management of mechanical engineering products, V.V. Fighters puts forward a number of demands. The following must be ensured: development of strategy and management criteria; availability of effective feedback to monitor the implementation of the quality management strategy; availability of reserves; taking into account the role of the human factor.

The scientist paid much attention in his works to the formation and functioning of quality systems; product quality planning; stimulating quality improvement; product certification.

As President International organization on standardization V.V. Boytsov was one of the initiators and participants in the creation of the ISO 9000 series of standards, which have become the most widespread in the world. He is a representative of the domestic scientific school, directly related to the development and implementation of Russian enterprises into practical activities systematic approach to quality management.

One of the domestic creators of the theory of quality management is Alexander Vladimirovich Glichev. He is the author of more than 300 scientific papers in the field of efficiency aircraft defense and civil purposes, reliability, quality management, standardization and certification. For 20 years he headed the Institute of Standardization of the USSR State Standard - VNIIS; elected President and Vice-President of the European Organization for Quality, headed Russian Academy quality problems.

Country - Russia (RU), number of patents - 10, received - 2008-2012

B23 - Metal-cutting machines; methods and devices for processing metals, not classified in other classes
B24 - Grinding; polishing
C12 - Biochemistry; beer; alcoholic drinks; wine; vinegar; microbiology; enzymology; obtaining mutations; Genetic Engineering
C22 - Metallurgy; alloys of ferrous or non-ferrous metals; processing of alloys or non-ferrous metals
E21 - Drilling soil or rocks; mining

Impregnated Diamond Drill Bit

The invention relates to the production of rock-cutting diamond tools, in particular impregnated diamond drill bits used when drilling wells with core sampling during exploration of mineral deposits....

Method for obtaining internal rectilinear and curved channels in parts

The invention can be used to obtain internal rectilinear and curved channels, including channels of great length, in monolithic parts. The friction stir welding tool is placed on the surface of the part and...

Device for friction welding of long parts

The invention can be used for friction welding using an intermediate insert of long parts, in particular railway rails, pipes, rods. A gripping mechanism is mounted on a frame with supporting elements for installing parts...

A method for individual selection of probiotic preparations containing lactobacilli and/or bifidobacteria for the elimination of opportunistic microorganisms isolated from a patient during testing for intestinal dysbiosis

The invention relates to biotechnology and medicine and can be used in bacteriological laboratories for individual selection of probiotic preparations containing lactobacilli and/or bifidobacteria for the elimination of opportunistic pathogens...

Orbital Friction Welding Device

The invention can be used for welding parts of arbitrary cross-sectional shape, including parts in the form of a body of revolution, in particular for welding blades to gas turbine rotor disks. There are 4 spindles in the hole 1, made with eccentricity...

Method for manufacturing cutting elements based on powders of superhard materials

The invention relates to the production of cutting elements including binders and powders of superhard materials. Powders of superhard materials of at least two grain sizes are used, while the powders of superhard materials have a larger...

A method for individual detection of antagonistic activity of probiotic preparations containing lactobacilli and/or bifidobacteria against opportunistic microorganisms isolated during the diagnosis of intestinal dysbiosis

Strains of opportunistic microorganisms (OPM) are isolated from the feces of the subject, then lactobacilli and/or bifidobacteria that are part of the probiotic preparation are isolated in pure culture. Determine the antagonistic activity of lactobacilli...

A method for individual assessment of the effectiveness of eubiotics, the main active principle of which is the strain of bacillus cereus ip 5832 (atcc 14893), against opportunistic microorganisms isolated from a patient during a study for intestinal dysbiosis

The invention relates to the field of medicine, namely microbiology, and can be used in bacteriological laboratories to detect the antagonistic activity of the Bacillus cereus strain IP 5832 (ATCC 14893). Carry out joint incubation in...

Method for manufacturing the working layer of an abrasive tool from powders of superhard materials

The invention relates to the field of abrasive processing and can be used in the production of abrasive tools with cutting grains from diamond powders, cubic boron nitride and other superhard materials and with a binder based on...

Friction stir welding method and friction stir welding tool

The invention can be used for permanently connecting parts with both longitudinal and closed circumferential seams. The probe 5 of the rotating welding tool is immersed in the joint of the parts to be welded until a welding force is created and...

Publications

In our country, and not only in ours, there are a huge number of inventors. Unfortunately, not all of them receive legitimate laurels for their creations due to the patent not being issued on time.

He entered the Moscow Aviation Institute in 1956, graduating in 1962 with a degree in mechanical engineering for anti-aircraft guided missiles.

During his time at MAI, he went through the path of a teacher - from an assistant to a professor at Department 104 “Aircraft Production Technology” (1977).

After defense doctoral dissertation in 1982 he was awarded the academic title of professor.

From 1988 to the present, he has been the head of department 104 “Technological design and quality management”.

On his initiative and with his direct participation, the department began to graduate in three specialties: mechanical engineer (specialization 160201); engineer-manager (specialty 05.22.01 “Quality Management”) and specialists (specialty 100101 “Service”).

He was part of a group of Higher School specialists who developed and introduced into the educational process the specialty “Quality Management”, which is taught at more than 150 universities in Russia, was formed with the participation of English and Dutch specialists and adapted with the European educational system.

Under his leadership, a scientific and methodological basis for the educational process of the department was created:

textbook for higher education educational institutions“Anthology of Russian quality” edited by professors Boitsov B.V. and Kryaneva Yu.V. (three printed reprints and one electronic edition);
monographs: “Philosophical and social aspects of quality” (Boitsov B.V., Kryanev Yu.V., Kuznetsov I.A.), “The concept of quality of life” and “The concept of quality of life: problems in the global and regional dimensions” (Boitsov B .V., Kuznetsov I.A., Elkin G.I.);
a series of publications in the specialty “Quality Management”.

He continued the traditions of the school of domestic mechanical engineering and the Institute of Mechanical Science of the Russian Academy of Sciences in probabilistic methods of calculating strength and durability. In these scientific areas, B.V. Boytsov. More than 160 works have been published in various publications, including monographs, textbooks, guidelines, GOSTs, for example:

The use of engineering plastics in the production of aircraft. Tutorial–M.: MAI, 1967 (co-author);
The use of engineering plastics in aircraft structures. Tutorial. -M.: Mechanical Engineering, 1971 (co-author);
Reliability of aircraft landing gear. Tutorial. -M.: Mashinostroenie, 1976;
Forecasting the durability of stressed structures. -M.: Mashinostroenie, 1985;
Design of passenger aircraft. Monograph. Ed. G.V. Novozhilova. -M.: Mechanical Engineering, 1991 (co-author);
Durability of hinged and bolted joints. -M.: Mechanical Engineering, 1996 (co-author);
Life cycle and sale of the aircraft. Ed. B.V. Boytsova and N.M. Kiseleva. -M.: MAI, 2005, (co-author).

He is the head of the department's scientific direction "Reliability and service life of aircraft structures." Under his scientific leadership, candidate and six doctoral dissertations were successfully defended.

Conducts a lot of work to introduce and promote modern achievements in the field of quality. He is one of the founders of the Academy of Quality Problems of the Russian Federation, consolidating specialists working in the field of quality problems.

In 2001, he was elected a member of the International Guild of Quality Professionals (CIS) and a corresponding member of the UK Institute of Quality Assurance (AIQA). The key ideas and activities of these organizations are the consolidation and intensification of the efforts of scientists and specialists in solving problems of quality of life, education, products and services. Ideas of quality of life permeate his publications in this area. The results of creative search are reflected in a number of fundamental works.

Boytsov B.V. is the editor-in-chief of the magazine “Quality and Life”.

A group of specialists - members of the Academy of Quality Problems, which includes B.V. Boytsov, developed GOST R “Provision of services in the field of training specialists in standardization, metrology, certification and quality management”, registered by Rosstandart.

The European Quality Organization in Russia established the European Quality Center, in which B.V. Boytsov is the Chairman of the Personnel Certification System.

A big place in the activities of Boytsov B.V. occupied by expert work. For many years he has worked on the expert councils “Mechanical Engineering”, “Mechanical Engineering and Metallurgy” of the Higher Attestation Commission of Russia. He worked for a long time on the expert council “Mechanical Engineering and Transport” of the Commission of the President of Russia on state awards in the field of science and technology.

He is the Chairman of the dissertation council D212.125.10 for awarding the degree of candidate and doctor of technical sciences in the following specialties:

05.07.02 “Design, construction and production of aircraft”;
02/05/23 “Standardization of product quality management”;
05.02.01 “Materials Science”;
02/05/08 “Mechanical Engineering Technology”;
05.07.03 “Strength and thermal conditions of aircraft.”

He does a lot of social work. He was elected as a deputy of the Leningrad Council of People's Deputies of Moscow in five convocations, Chairman of the standing commission of the Council of People's Deputies on public education. In 1988, he was elected a member of the Board of the Association of Technologists of the USSR, and was an associate member Public Chamber under the President of Russia B.N. Yeltsin.

Completed a number of retrainings to improve his skills. In 1990, he graduated from the summer semester “Educational Structures of the USA” at the University of Washington. In 1997, he received training in the UK and South Africa on standardization and quality management of products and services. He completed the course and received a diploma “Peculiarities of the work of short-term creative teams of the international humanitarian movement “Lions””.

For his great personal contribution to the development of industry and higher education, he was awarded:

Order of the Red Banner of Labor (1976);
Order of Peter the Great, 1st degree “For merits and great personal contribution to the development and strengthening of the Russian state” (2008),
cross “Tith” (2008);
medal "For Valiant Labor"
two silver medals from VDNKh,
medals “For Merit in Standardization”, “200 Years of the Ministry of Defense” (2008);
medal I.A. Ilyin “For the development of Russian thought” (2007);
medals named after V.P. Glushko “For the development of special technologies for rocketry”, named after K.E. Tsiolkovsky, named after S.P. Koroleva, “40 years of Yu.A.’s flight. Gagarin into space", "For services to astronautics";
anniversary medal “80 years of the Civil Air Fleet”;
medals “Veteran of Labor” and “In Memory of the 850th Anniversary of Moscow” (1997);
diploma of the Presidium of the Supreme Soviet of the RSFSR (1989),
diploma of honor from the Ministry of Higher vocational education (2003);
a diploma from the Ministry of Industry and Trade of Russia and the Federal Agency for Technical Regulation for many years of conscientious work, personal contribution to the development of the domestic aircraft industry, training in the field of quality management and in connection with the 70th anniversary of his birth (2008);
honorary badges “For merits in the standardization of the USSR”, “Excellence in Aeroflot”, “Excellence in Higher School”, “For excellent success in work” - the Ministry of Higher and Secondary special education"(1978, 1980), "For services in the field of standardization and quality named after V.V. Boytsov" of the Ministry of Industry and Energy of the Russian Federation.

He is a laureate of the USSR State Prize in the field of science and technology “For the development of methods and the creation of systems for ensuring the service life of machines” (1989); Government awards Russian Federation in the field of education “For the creation of a national system of training, retraining and certification of specialists in the field of quality management” (2007), prize S.I. Mosin "For significant contribution to the development of science and technology for military purposes, the creation of technologies and equipment that have dual use"(2005), prize named after the 25th anniversary of MAI.

He has the honorary titles of Honored Scientist of Russia and Honorary Worker of the Higher School of Russia.

Professional retraining teaching staff to perform a new type professional activity in the field of higher education pedagogy, diploma No. PP No. 712914, Military University (faculty of retraining and advanced training. Organization and content of research activities of teachers in education, 72 hours, certificate, Academy of Advanced Training and professional retraining education workers. Pedagogy and psychology of higher education. Contents and methods of teaching general professional and special disciplines. Profile: linguistics, 72 hours, certificate, Federal State Budgetary Educational Institution of Higher Education "Russian State Social University". Innovative quality assurance models higher education in a modern educational complex., 72 hours, certificate, Federal State Budgetary Educational Institution of Higher Education "Russian State Social University". Strategies for mastering and using a foreign language in a multicultural world, certificate No. 1, Federal State Autonomous Educational Institution of Higher Professional Education "National research university" graduate School economy. Modern trends and technologies in teaching in English for special purposes, certificate No. 84, Federal State Autonomous Educational Institution of Higher Professional Education "National Research University" Higher School of Economics. Expert in the field of higher and secondary vocational education, diploma No. KR No. 003079, Federal State Budgetary Educational Institution of Higher Education "Russian State Social University". Implementation of a professionally competent approach within the framework of the discipline "Foreign Language", 72 hours, certificate, Federal State Autonomous Educational Institution of Further Professional Education "Academy of Advanced Training and Professional Retraining of Education Workers". Application of modern electronic educational technologies V educational process, 72 hours, certificate, Federal State Budgetary Educational Institution of Higher Education "Russian State Social University". Teaching methods for higher education programs using e-learning technologies, 52 hours, certificate, Federal State Budgetary Educational Institution of Higher Education "Russian State Social University". The evolution of online teaching of foreign languages: the use of hybrid forms of learning and innovative teaching practices, certificate, Federal State Autonomous Educational Institution of Higher Professional Education "National Research University" Higher School of Economics. Key directions for the implementation of state policy and legal regulation in the field of higher education, 72 hours, certificate No. 180000400737, Federal State Budgetary Educational Institution of Higher Education "Russian State Social University". Innovative technologies implementation of HE programs, 160 hours, certificate No. 180000405834, Federal State Budgetary Educational Institution of Higher Education "Russian State Social University". Information and communication technologies in project, educational and research activities of teachers and students, 72 hours, certificate No. 180000407660, Federal State Budgetary Educational Institution of Higher Education "Russian State Social University". Teacher vocational training, vocational education and further professional education, diploma No. 772400002838 dated 02.27.2018, Federal State Budgetary Educational Institution of Higher Education "Russian State Social University". Traditions and innovations in teaching foreign language at a non-linguistic university, 16 hours, certificate No. AAA 180879652 dated 04/06/2018, MGIMO (university) of the Ministry of Foreign Affairs of Russia.